Quell, from NeuroMetrix. Transcutaneous electrical nerve stimulator device fits in band worn around upper calf. "Stimulates sensory nerves, which leads to the release of endogeno (Wearable Technology Gadgets)
2017:A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine | Anesthesiology | ASA Publications
Low-dose naltrexone or LDN, a prescription drug classified as an opioid antagonist, may be one of the rare drugs that actually helps your body heal itself. It blocks opioid receptors and helps activate your body's immune system.
Light -- not pain-killing drugs -- used to activate brain's opioid receptors
Oxycodone is a strong narcotic pain-reliever and cough suppressant similar to morphine, codeine, and hydrocodone. The precise mechanism of action is not known but may involve stimulation of opioid receptors in the brain
Pharmacology Overview Five topics related to the general pharmacology of opioids are reviewed in the first part of this chapter: (1) opioid receptors; (2) functions of opioids at receptors; (3) consequences of repeated administration and withdrawal of opioids; (4) the affinity, intrinsic activity, and dissociation of opioids from receptors; and (5) general characteristics of abused opioids. These topics are followed by a detailed review of the general and applied pharmacology of…
Opioids applied in a topical cream that directly target the peripheral opioid receptors (which grow in inflammatory pain sites to attract natural endorphin compounds for pain relief and immune enhancement) may have advantages relative to oral opioids.