[MEGALOBLASTIC ANEMIA]. Coarse basophilic stippling is also a morphologic feature of MA but not specific to this disease and can be seen in other disorders including lead poisoning, sideroblastic anemia, thalassemia, certain hemoglobinopathies, and pyrimidine 5` nucleotidase deficiency. Defective DNA synthesis is also seen in congenital deficiency of certain enzymes including dihydrofolate reductase and methyltransferase.
Fatty Acid Oxidation Beta Oxidation in mitocondria @ Acyl- vs Acetyl CoA I put this in here b/c is important for production of Succinyl Co A (Sideroblastic Anemia) AND Fatty Acid break is loosely related to this by methymaonly Co A,
Correlate with Pathophysiology! A 44 year old woman with worsening fatigue, tingling and numbness in bilateral lower extremities. Past Medical history of gastric bypass surgery and current use of dentures!