Alexander Gow & Cherie Southwood, Inner ear from a null mouse. 24 Claudin genes have been found in mammals. Claudin 11 deficient mice show deafness because of the disappearance of tight junctions from the basal cells of the stria vascularis
Tight junctions are a type of cell junctions that play a role in cell adhesion and permeability of paracellular barrier. This Buzzle post elaborates on where these junctions are found, their structure as well as their function.
IBD mechanism Ecoli adherrance and lining - tight junction mechanisms of dsyfunction. A TON OF GEEK in here.